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US orders government to prioritize domestic drug supply chain

September by September
12/08/2020
in Blog
Chính phủ Hoa Kỳ ưu tiên tập trung vào chuỗi cung ứng thuốc trong nước

The pharmaceutical supply chain was under the microscope before the coronavirus pandemic, its frailty and dependence on overseas companies made apparent by drug shortages and contamination concerns. In 2018, the U.S. imported 95% of its ibuprofen from China, in addition to 91% of the U.S. supply of hydrocortisone, 70% of its acetaminophen, 40% to 45% of its penicillin and 40% of its heparin.

But the crippling impact of coronavirus’ spread on the U.S. economy exposed further weak links, as hospitals ran short of personal protective equipment, ventilators and vital medicines. While some shortages have now been resolved, the nation’s experience has appeared to make the Trump administration even more eager to bring as much manufacturing back to the U.S. as possible.

During a Thursday speech in Ohio at a washing machine factory, President Donald Trump said he had signed an executive order mandating U.S. government agencies to purchase “all essential medicines that we need from American sources.” The text of the order didn’t clarify exactly which medicines are essential, but noted that the “list” of medicines would be determined by the Food and Drug Administration within 90 days.

The directive, however, would apply only to medicines that the government buys directly, which represent a small portion of the drugs used in the U.S.

Notably, the requirement to buy American would not apply when U.S. agency heads determine there aren’t sufficient domestic quantities of the relevant drug to purchase, or when doing so would cause procurement costs to rise by 25%.

Additionally, the order aims to “support advanced manufacturing processes,” such as continuous manufacturing, a newer drug production technique that, while common in most sectors, isn’t widely adopted among drugmakers. Another section in the document calls on the Environmental Protection Agency to quickly permit approvals to build new drug manufacturing sites.

Momentum towards the executive order like the one announced Thursday has been building. In recent months, lawmakers on Capitol Hill have introduced a number of bills aimed at revamping the biopharmaceutical supply chain.

The Trump administration, meanwhile, awarded in May an $812 million contract to a little-known drugmaker called Phlow, so it could make ingredients and doses of generic drugs currently manufactured in India and China. Last week, the government signed a letter of intent to loan Eastman Kodak $765 million to fund the company’s pivot into drug manufacturing.

“The ‘Buy American’ executive order could disrupt the global pharmaceutical supply chain, jeopardizing our ability to respond to the current crisis and potentially leading to major long-term supply chain disruptions, including shortages,” Stephen Ubl, head of the drug lobby PhRMA, said in a statement.

Source: Supplychaindive
Tags: Drug supply chainus

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